NEJM This Week - Audio Summaries

Featuring articles on clonal hematopoiesis and coronary heart disease, pertuzumab plus trastuzumab in HER2-positive breast cancer, long-term results of the PIVOT prostate-cancer trial, diet and total and cause-specific mortality, Crimean–Congo hemorrhagic fever in Spain, and the march of science; a review article on amyotrophic lateral sclerosis; a case report of a pregnant woman with endocervical carcinoma; and Perspective articles on targeting unconscionable prescription-drug prices, on the economics of indication-based drug pricing, and on the chair grant.

Featuring articles on the effect of overweight and obesity in 195 countries, endometriosis-associated pain management with elagolix, the declining risk of sudden death in heart failure, CD55 and protein-losing enteropathy, and the macrophage and the heart; a review article on master protocols; a Clinical Problem-Solving article describing beating, fast and slow; and Perspective articles on undermining genetic privacy, on home-to-home time, on patient-reported outcomes, and on preserving the Fogarty International Center.

Featuring articles on air pollution and mortality in the Medicare population, electrical direct current vs. escitalopram for depression, levothyroxine in older adults with subclinical hypothyroidism, and antibiotics for skin abscess; review articles on subclinical hypothyroidism and on the irritable bowel syndrome; a case report of a man with weight loss, confusion, and skin lesions; and Perspective articles on prospects for health care reform in the U.S. Senate, on FDA approval of valbenazine for tardive dyskinesia, on machine learning and prediction in medicine, and on decision aids and elective joint replacement.

Featuring articles on nivolumab in untreated lung cancer, a cell-culture influenza vaccine, lying flat versus sitting up after acute stroke, the glucocorticoid-sparing effect of benralizumab in asthma, and understanding early events in breast cancer; a review article on post-traumatic stress disorder; a case report of a woman with leg numbness and weakness; and Perspective articles on the AHCA, on the first hundred days for health care, on effective legislative advocacy, and on incarceration and health.