Question and Response 61

New College-Style Sweatshirt!  And Spooky Chemistry Shirts Are Back! 

In this episode of 'Chemistry for Your Life,' hosts Melissa and Jam address a variety of intriguing listener questions. They cover topics such as the chemical processes behind self-tanners and why early formulations could result in uneven appearances, the unique properties and phase changes of dry ice, and the complexities surrounding high fructose corn syrup. The discussion spans the importance of physical chemistry, the societal pressures linked to beauty standards, and the exfoliating benefits of chemical peels. Positive feedback from viewers is acknowledged, and the hosts encourage further engagement via questions and Patreon membership.

00:00 Introduction and Episode Overview
00:35 Welcome to Chemistry for Your Life
01:26 Listener Questions: Tanning and Self-Tanning
06:54 Chemistry Behind Self-Tanners
08:09 More Listener Questions: Self-Tanner Reactions
11:13 The Smell of Self-Tanners
12:09 Scariest Chemistry Class
12:36 Understanding Small Particle Physics
13:33 Physical Chemistry and Thermodynamics
14:41 Chemical Peels Explained
15:34 Is Fructose Bad for You?
16:29 The Science of Dry Ice Sublimation
22:09 Listener Questions and Comments
24:15 Supporting the Show and Community Shoutouts

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#196

New College-Style Sweatshirt!  And Spooky Chemistry Shirts Are Back! 

Melissa and Jam explore the fascinating chemistry behind self tanners. They take listeners on a journey from the discovery of the key sugar in self tanners in the 1960s by Dr. Eva Wittgenstein to the present-day scientific understanding. The episode delves into the Maillard reactions, typically known for browning food, explaining in simple terms how similar reactions color the skin when self tanners are used. Additionally, the hosts discuss the molecular structure of carbohydrates, the generation of free radicals, and the temporary UV sensitivity following self-tanner application. Interactive elements like pop quizzes and listener shout-outs keep the discussion engaging and educational, while also touching on recent studies and encouraging community support. The episode is a blend of fun facts, thorough biochemistry, and practical advice for achieving a safe, sun-kissed look.

00:00 Introduction to Tanning and Self-Tanners
00:41 The Chemistry Behind Self-Tanners
03:14 History and Discovery of Self-Tanners
04:34 The Maillard Reaction Explained
13:17 Debate on the Maillard Reaction in Self-Tanners
24:40 Application and Effects of Self-Tanners
28:15 The Importance of Sunscreen
28:55 Fun Facts About Tanning
30:06 Pop Quiz Time!
31:15 Rewards and Treats
31:57 Dr. Pepper Shake Discussion
34:22 Quiz Results and Reflections
41:11 Listener Questions and Bonus Episode Tease
42:22 Merchandise Shoutout and Closing Remarks

1. https://pubs.acs.org/doi/10.1021/acsomega.2c06124
2. https://pubsapp.acs.org/cen/whatstuff/stuff/7824scit2.html
3. https://www.compoundchem.com/2014/08/07/faketan/
4. https://cen.acs.org/articles/96/i4/Whats-sunless-tanner-and-how-does-it-impart-that-faux-glow.html
5. https://www.sciencedirect.com/science/article/abs/pii/S0143720822003709
6. Garrett & Grisham’s Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

Thanks to our monthly supporters

• Scott B
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• J0HNTR0Y
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• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
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• Hunter Reardon

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#048 Rebroadcast

New College-Style Sweatshirt!
And the Ghost Halloween Design is Back!

This week, Melissa and Jam dive into spiciness. What is it? Is it a flavor? Is it a feeling? Is it both? Is it more? Why can some people handle more than others? Does spiciness have any benefits?

References from this episode

1. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/vanilloids
2. Solomon’s Organic Chemistry 11th edition
3. Analogues of Capsaicin with Agonist Activity as Novel Analgesic agents; Structure-Activity Studies 2. The Amide Bond “B-Reigion” byWalpole et. al
4. Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues by Walpole et. al
5. Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study by Ohbuchi et. al
6. The Art and Science of Organic andNatural Products Synthesis - by Nicolau et. al
7. https://www.acs.org/content/acs/en/pressroom/reactions/videos/2015/why-are-hot-peppers-hot-and-how-milk-helps.html

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• Suzanne Phillips
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• Lyn Stubblefield
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#196

New College-Style Sweatshirt!

Melissa and Jam delve into the science behind ibuprofen, exploring why it takes around 30 minutes to work. The discussion covers the chemistry of ibuprofen, including the concept of chiral molecules and enantiomers—molecules with mirror-image forms—highlighting how only one form of ibuprofen works effectively. The episode explains why both forms are included in the medication due to production challenges and discusses recent findings about ibuprofen's potential in cancer treatment. Additionally, the show features various fun facts about ibuprofen, aspirin comparisons, environmentally friendly production methods, and more.

00:00 Introduction and Episode Overview
05:07 Chemistry Lesson: Handedness of Molecules
17:52 Ibuprofen's Chiral Nature and Its Effects
19:15 The Racemic Mixture of Ibuprofen
24:06 The Wastefulness of Chemistry
24:29 Challenges of Purifying Enantiomers
25:16 Economic and Environmental Considerations
26:28 Understanding Ibuprofen's Handedness
27:26 The Debate on Enantiomer Separation
34:45 Fun Facts About Ibuprofen
39:55 Green Chemistry and Ibuprofen
45:42 Community and Closing Remarks

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/
2. https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf
3. https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article
4. https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

Thanks to our monthly supporters

• Scott B
• Jessie Reder
• Ciara Linville
• J0HNTR0Y
• Jeannette Napoleon
• Cullyn R
• Erica Bee
• Elizabeth P
• Sarah Moar
• Rachel Reina
• Letila
• Katrina Barnum-Huckins
• Suzanne Phillips
• Venus Rebholz
• Lyn Stubblefield
• Jacob Taber
• Brian Kimball
• Emerson Woodhall
• Kristina Gotfredsen
• Timothy Parker
• Steven Boyles
• Chris Skupien
• Chelsea B
• Bri McAllister
• Avishai Barnoy
• Hunter Reardon

Check out our website at chemforyourlife.com

Watch our episodes on YouTube

Find us on Instagram, Twitter, and Facebook @ChemForYourLife